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Friedrich Miescher
He discovered DNA. He didn’t just know it, he started working with white blood cells and called it nuclein. This is very important and helps us because it taught us what we were made of and it taught us who we are and why we are the way we are. -
Thomas Morgan
He used research research using fruit flies.This helped us because he came up with many important discoveries of genetics and chromosomal inheritance. -
Barbara McClintock
She did pioneer work in plant genetics. This was important because her work determined the mechanisn for transposition in corn. -
George Beadle
Demonstrated the “one gene one protein” hypothesis. This hypothesis helped us because it was the idea that genes act through the production of enzymes, with each gene responsible for producing a single enzyme that in turn affects a single step in a metabolic pathway. -
Oswald Avery
Showed that Fred Griffith’s “transforming principle" was DNA by doing a series of experiments using strains of Pneumococcus bacteria, which causes pneumonia. This helped us today becuase he gave us proof that it was really DNA. Not just information that could somehow be transferred between different strains of bacteria. -
Erwin Chargaff
He discovered base pairs. The first pair is Adenine and Thymine. The second pair Guanine and Cytosine.
This is important because base pairs are the building blocks of the DNA double helix and contribute to the folded structure of DNA. -
Rosalind Franklin
She produced the X-ray crystallography pictures of BDNA.
This was important because it was used to determine the structure of double-stranded DNA. -
Linus Pauling
He proposed a triple-stranded helix structure for DNA. This taught us a structure of DNA in which three oligonucleotides wind around each other and form a triple helix. In this structure, one strand binds to a B-form DNA double helix through Hoogsteen or reversed Hoogsteen hydrogen bonds. -
Hershey-Chase
They did the Hershey-Chase blender experiment.l.
The significance of this experiment was that it proved phage DNA, and not protein, was the genetic material. -
James Watson
He built the first accurate model for DNA with Francis Crick.
This was important because it finally showed people what DNA actually looked like. -
Francis Crick
He came up with the double helix structure for DNA with James Watsons and also proposed the Central Dogma and Adaptor Hypothesis. It helped us becuase we learned what DNA looked like. -
Seymour Benzer
He realized that crossing over could be within the jean. This helped us because most people thought that genes resembled beads in a string. That is, jeans were indivisible and crossing over could only occur between the jeans.
