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Jamestown is founded on the coast of Virginia by 100 English settlers
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French explorer, Samuel de Champlain, founds the colony of Quebec.
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An epidemic of smallpox, brought by Europeans, kills many native Americans on the New England coast
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Pilgrims from England found an English Colony in Plymouth, Massachusetts
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Henry Hudson, exploring for the Netherlands, claims land that will become New Netherland
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The Duke of York drives out the Dutch in New Netherland. The Duke of York claims the colony for England and renames it New York.
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King Phillip's War begins in Colonial villages of Massachusetts, between colonists and Native Americans.
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Sieur de la Salle explores the lower Mississippi Valley river, and claims the valley for France and names it Louisiana in Honor of the French King Louis XIV.