HISTORY OF GENETICALLY ENGINEERED VACCINES

By vincenthong

  • Genentech is founded

    Genentech is founded
    Venture capitalist Robert A. Swanson, biochemist Dr. Herbert W. Boyer (pioneered recombinant DNA technology) founded biotechnology company, Genentech in South San Francisco in one rented building and two staff members

  • E-Coli vaccine is produced

    E-Coli vaccine is produced
    U.S. Dept of Agriculture scientists turned to recombinant DNA technology, collaborated with scientists from Genentech, a private company; inserted a bioengineered plasmid containing the gene for VP3 into Escherichia coli bacteria which grew obeying orders from the guest DNA, mass-producing the VP3 proteins for the vaccine.

  • First genetically engineered vaccine announced

    First genetically engineered vaccine announced
    First genetically engineered vaccine announced: first effective subunit vaccine for any animal or human disease using gene splicing; designed to prevent hoof and mouth disease (FMD)

  • Human Insulin is marketed

    Human Insulin is marketed
    marketed First recombinant DNA drug, human insulin (licensed to Eli Lilly and Company)

  • Human Growth Hormone is approved

    Human Growth Hormone is approved
    received approval from U.S. Food and Drug Administration (FDA) to market first product, Protropin® (somatrem for injection) growth hormone for children with growth hormone deficiency (first recombinant pharmaceutical product manufactured, marketed by biotechnology company)