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Barbara McClintock
1902-1992.
She worked on transposition in corn chromosomes. Her work was fairly well known but little understood until the molecular basis was shown in the 1970’s. She was awarded a Nobel Prize for Physiology and Medicine in 1983. -
Oswald Avery
1887-1955.
In 1913 he published a clinical study of tuberculosis bacterium. the first to isolate acids from pneumococcus. Concluded that DNA is a transforming principle, and published the results in 1944. -
Arthur Kornberg
1918-1959.
He isolated DNA polymerase I and show that life (DNA) can be made in a test tube. HE isolated and identified over a hundred enzymes used in metabolic reactions. -
Hermann Muller
1890-1967.
In the 1920’s he performed his research showing that X-rays could induce mutations. He worked on X-rays and other mutagens like UV and mustard gas. -
Evelyn Witkin
1921-1977.
She identified a strain of E. coli bacteria known as B/r that was no more resistant to radiation than the parental B strain. This was the first time mutations conferring resistant to radiation had been isolated. -
Seymour Benzer
1921-2007.
He hatched a plan to get inside the gene by using bacteriophage with mutant rII genes. He and his graduate student, Ronald Konopka, were the first to find a gene that controls an organism’s sense of time. -
Hershey-Chase
1908-1997.
They did the hershey-chase blender experiment that proved phage DNA, and not protein, was the genetic material. in 1946 Hershey discovered that phage can recombine when co-infected into a bacteria host. -
Erwin Chargaff
He isolated DNA from different organisms and measured the levels of each of the four nitrogenous bases -
Rosalind Franklin
SHe was born in London, England. in 1951 she produced the X-ray crystallography pictures of BDNA. She used two different fibers of DNA, one more highly hydrated than the other. She then deduced the basic dimensions of DNA strands, and the phosphates were on the outside of what was probably a helical structure. She died from cancer in 1958. -
JAmes Watson and Francis Crick
1916-1992.
They solved the structure of DNA.In 1953 they published the first accurate model of the DNA molecule.
