-
Period: to
DNA Discovery
-
Frederick Griffith (1879-1941)
a British bacteriologist who discovered what the central role of DNA in heredity was. He discovered the transforming principle in pneumococcus bacteria. Fredrick Griffith and Oswald Avery were the key researchers for this discovery. His famous experiment "Griffith's experiment was one of the first experiments suggesting that bacteria are capable of transferring genetic information through a process known as transformation. -
Oswald Avery (1877-1955)
an American bacteriologist who identified a complex carbohydrate called polysaccharide, and showed that it could stimulate production of antibodies as an immune response. It was the first immune response seen in anything but a protein. -
Erwin Chargaff (1905-2002)
an American biochemist and author. He discovered the key facts needed to determine the structure of DNA.Chargaff's Rules. He demonstrated three rules, now known as Chargaff's Rules, which state that in DNA:1. the number of adenine (A) residues always equals the number of thymine (T) residues;2. the number of guanine (G) residues always equals the number of cytosine (C) residues;3. the number of purines (A+G) always equals the number of pyrimidines ( -
Rosalind Elsie Franklin
a British biophysicist and X-ray crystallographer who made critical contributions to the understanding of the fine molecular structures of DNA. One of Rosalind Franklin's important contributions to the Crick and Watson model was her lecture at the seminar in November 1951, where she presented to those present, among them Watson, the two forms of the molecule, type A and type B, and her position whereby the phosphate units are located in the external part of the molecule. -
Alfred Hershey and Martha Chase
The Hershey–Chase experiments were a series of experiments conducted by Alfred Hershey and Martha Chase that helped to confirm DNA is the genetic material. DNA had been known to biologistssince 1869, but a few scientists still assumed at the time that proteins carried the information for inheritance. Hershey and Chase showed that when bacteriophages, which are composed of DNA and protein, infect bacteria, their DNA enters the host bacterial cell, but most of their protein does not. -
Watson and Crick
"Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid" was an article published by Francis Crick and James D. Watsonin the scientific journal Nature that described the discovery of the double helix structure of DNA.Although Watson and Crick were first to put together all the scattered fragments of information that were required to produce a successful molecular model of DNA, their findings had been based on data collected by researchers like Roslind Franklin