DNA

By laceyhedrick

  • Griffith

    Griffith
    Injected mice with heat-killed, disease-causing bacteria that “transformed” harmless bacteria into ones that can cause disease.“transforming factor” lead to question that maybe DNA carried the genetic information.

  • Chargaff

    Taking samples of DNA from various organisms and measuring the percentages of nucleotides present. Chargaff’s Rule; base pairing: adenine pairs with thymine and guanine pairs with cytosine-though he did not know why!

  • Avery

    Followed/repeated Griffith’s experiment. Yes, DNA stores and transmits genetic information from generation to the next.

  • Linus Pauling and Robert Corey

    Taking samples of proteins from various organisms. The structure of a class of proteins is a helix.

  • Hershey-Chase

    Used different radioactive markers to label the DNA and proteins of bacteriophages. Genetic material was DNA, not protein.

  • Franklin

    Using X-ray technique to take pictures of DNA. Developed the technique called X-ray diffraction, which lead to the discovery of the double helix shape of DNA.

  • Watson and Crick

    Be researching others work and manipulating models. DNAs structure is a double helix.

  • Brenner

    Measurements, observations, and repeating of others discoveries. Showed the existence of messenger RNA (mRNA).

  • Gilbert

    Measurements, observations, and repeating of others discoveries. Developed methods to read the DNA sequence.