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Leonardo was born in the Tuscan hill town of Vinci.
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Leonardo da Vinci's life
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He becomes an apprentice in Veroccio's workshop.
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His earliest known dated work is a drawing in pen and ink of the Arno valley, drawn on 5 August 1473.
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Leonardo worked in Milan from 1482 until 1499. He painted the Virgin of the Rocks and The Last Supper for the monastery of Santa Maria delle Grazie.
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In the spring of 1485, Leonardo travelled to Hungary on behalf of Ludovico to meet Matthias Corvinus, and was commissioned by him to paint a Madonna.
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Leonardo's most famous painting of the 1490s is The Last Supper, commissioned for the refectory of the Convent of Santa Maria della Grazie in Milan
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At the start of the Second Italian War in 1499 Leonardo fled Milan for Venice.
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Leonardo da Vinci is thought by some to have begun painting the Mona Lisa in 1503 or 1504 in Florence, Italy.
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From September 1513 to 1516, under Pope Leo X, Leonardo spent much of his time living in the Belvedere in the Vatican in Rome.
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In 1516, he entered Francis' service, being given the use of the manor house Clos Lucé, now a public museum, near the king's residence at the royal Château d'Amboise.
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Leonardo died at Clos Lucé, on 2 May 1519 at the age of 67. The cause is generally stated to be recurrent stroke.