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The U.S. Equal Employment Opportunity Commission extended workplace protections under the Americans with Disabilities Act to cover discrimination based on genetic information.
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A physical map uses sequence-tagged sites (STSs) as markers to order large segments of DNA.
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The first international strategy meeting on human genome sequencing drew scientists from the countries in Europe, North America, and Asia funding human genome sequencing projects.
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Scientists created a map showing the locations of ESTs (expressed sequence tags) representing fragments of more than 16,000 genes from throughout the genome.
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In 1996, the National Human Genome Research Institute funded pilot projects to find efficient strategies for completely sequencing the human genome.
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A Task Force on Genetic Testing was created by the NIH-DOE Working Group on Ethical, Legal, and Social Implications of Human Genome Research to review genetic testing in the United States and make recommendations to ensure the development of safe and effective genetic tests.
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In October 1998, HGP researchers released a gene map that included 30,000 human genes, estimated to represent approximately one-third of the total human genes.
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In December 1998, the first genome sequence of a multicellular organism, the roundworm Caenorhabditis elegans, was completed.
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In March 1999, HGP participants advanced their goal of obtaining draft sequence covering 90 percent of the human genome to 2000, a year and a half before projected previously. Full-scale human genome sequencing began.
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In December 1999, the HGP completed the first finished, full-length sequence of a human chromosome - chromosome 22. This accomplishment demonstrated the power of the HGP method of clone-by-clone sequencing to obtain large amounts of highly accurate sequence.
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In March 2000, U.S. President Clinton and U.K. Prime Minister Tony Blair stated that raw, fundamental data about human genome sequence and its variations should be freely available.
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The Human Genome Project international consortium published a first draft and initial analysis of the human genome sequence. The draft sequence covered more than 90 percent of the human genome. One surprise is that the estimated number of genes was lower than expected, just 30,000-35,000.
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Researchers identified a gene on chromosome 1 associated with a hereditary form of prostate cancer. The work was a collaboration between researchers at the National Human Genome Research Institute, Johns Hopkins Medical Institutions, and The Cleveland Clinic.
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The International Human Genome Sequencing Consortium announced the successful completion of the Human Genome Project more than two years ahead of schedule and under budget.
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In April 1953, a paper appeared in the journal Nature that proposed a double helix structure for deoxyribose nucleic acid DNA. Determining the molecular structure of the gene was one of the most significant achievements in all of science.
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The United States Congress passed a resolution setting aside April 25th as National DNA Day. The date was chosen to mark the 50th anniversary of the publication of the landmark paper by Francis Crick and James Watson describing the double helix model of DNA and the recent official completion of the Human Genome Project.