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Feb 2, 1300
Roger Bacon used a convex lense as a magnifying glass
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Feb 2, 1485
Leonardo Da Vinci used glass lenses to study small objects
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Further development of compound microscope
Done by Robert Hooke, including the use of the iris diagram. He kept detailed records of his observations. -
"Utricles"
Martello Malpighi stated that all plants are built of chambers. ('Utricles') -
Discovering uni cellular organisms
Anton van Leeuwenhoek described uni cellular organisms from his observations of a drop of stagnant rain water. He discovered more uni cellular organisms when looking at water soaked peppercorns. -
Bacteria is discovereed
Leeuwenhoek discovers bacteria from his observations on saliva. -
No serious work in the 1700's
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Animals are plants are made of the same cells
This was discovered by Rene Dutrochet -
Cell Nucleus theorised
Robert Brown noted that the cells of orchids he was observing contained a structure inside the shell. He called this the nucleus. -
Cell theory formulated
Matthias Schleiden and Theodor Schwann formulated a theory that all living matter is comprised of small units called cells. -
Cell theory continues to come together.
Rudolf Virchow stated that 'where a cell exists there must be a pre existing cell, just as the animal only arises from the animal and the plant only from a plant.' -
Technology improves
Carl Zeiss and Ernst Abbe produced the first oil immersion objectives. Images could be magnified over 1000x. -
Cell division discovered
Walther Flemming described mitosis from observations on living and stained cells. -
First electron microscope
Built by Ernst Ruska. This paved the way for further development in this field. The details of internal cell structure was revealed using these technologies. -
Continued technological advancements
Throughout the rest of the 20th and into the 21st century microscope technology has continued to progress to extreme lengths. This allows incredibly detailed study of cells.