Cancer Treatments and Prevention

Early work in cell division by Carl Naegeli

Dec 31, 1844

Plant Cell Division Described Early work to describe cell division. "Walther Flemming (1843-1905)." (n.d.). Retrieved from https://www.dnalc.org/view/16235-Biography-7-Walther-Flemming-1843-1905-.html

All Cells Come from Cells-Cancer Cells Included (Virchow)

Dec 31, 1858

Virchow history, All Cells Come from Cells Wagner, R. P. (1999, March 1). Rudolph Virchow and the genetic basis of somatic ecology. Genetics, 151, 917-920. Retrieved from http://www.genetics.org/content/151/3/917

Cigarette Tax for Civil War funding

Jan 1, 1864

Brief Cigarette Tax History Shows taxes on cigarettes came before widely accepted knowledge of negative health impacts. "Cigarette taxes." (n.d.). Retrieved from http://taxfoundation.org/tax-topics/cigarette-taxes

Mitosis Processes Published

Jan 1, 1882

Walther Flemming background informationZellsubstanz, Kern und Zelltheilung (Cell substance, nucleus and cell division) published by Walther Flemming "Walther Flemming (1843-1905)." (n.d.). Retrieved from https://www.dnalc.org/view/16235-Biography-7-Walther-Flemming-1843-1905-.html

White Mutation by Thomas Hunt Morgan

Dec 31, 1910

Thomas Hunt Morgan mutation discovery Lewis, E. B. (1998, April 20). Thomas Hunt Morgan and his legacy. Retrieved from http://www.nobelprize.org/nobel_prizes/medicine/laureates/1933/morgan-article.html

Mouth Cancer Linked to Smoking

Jan 1, 1915

Cites 1915 study about mouth cancer Schrek, R., Baker, L. A., Ballard, G. P., & Dolgoff, S. (1950). Tobacco smoking as an etiologic factor in disease. I. Cancer. Cancer Research, 10, 49-58. Retrieved from http://cancerres.aacrjournals.org/content/10/1/49.full.pdf

World War II Start

Sep 1, 1939

Chart of Tobacco Consumption over Time World War II coincided with a spike in tobacco consumption by Americans, which led to the 20 years of highest tobacco consumption in the US. Burns, D. M., Lee, L., Shen, L.Z., Gilpin, E., Tolley, H. D., Vaughn, J., & Shanks, T. G. (2015). Cigarette smoking behavior in the United States. In National Cancer Institute (Ed.), Smoking and Tobacco Control Monograph No. 8. (pp. 13-112

America's Highest Level of Cigarette Smoking

Period: Jan 1, 1940 to Dec 31, 1965

Diagnosis of Uterine Cancer by the Vaginal Smear published

Jan 1, 1943

Pap Smear Book Published Shepard, E. M. (2011, June 29). George Papanicolaou: Development of the pap smear. Retrieved from http://weill.cornell.edu/archives/blog/2011/06/george-papanicolaou-development-of-the-pap-smear.html

Smoking linked to lung cancer

Feb 20, 1950

Smoking linked to lung cancer "Inside the Tobacco Deal." (n.d.). Retrieved from http://www.pbs.org/wgbh/pages/frontline/shows/settlement/timelines/fullindex.html

No Cervical Cancer Found in Nurses

Dec 31, 1952

“Cervical Cancer in Virgins.” (n.d.) Retrieved from http://www.cancerresearchuk.org/about-cancer/cancers-in-general/cancer-questions/cervical-cancer-in-virgins No Cervical Cancer Found in Nuns.

Thalidomide Taken off Market

Dec 31, 1962

The thalidomide episode is a situation that led to the FDA having more stringent rules for new drugs and slows the movement of drugs from research to widespread use. Thalidomide, used to treat morning sickness, caused malformations and death of babies. <a href='http://guides.main.library.emory.edu/c.php?g=50422&p=32503 "All Americans will pull together...The federal government's evolving role in dealing with disaster: Thalidomide drug crisis 1960s." (n.d.). Retri9' >Thalidomide Information</a>

Cigarette Tax in all States

Dec 31, 1969

Cigarette Tax informationAll states have a cigarette tax. "Cigarette taxes." (n.d.). Retrieved from http://taxfoundation.org/tax-topics/cigarette-taxes

(Public Health Cigarette) Smoking Act Becomes effective

Apr 1, 1970

Public Health Cigarette Smoking Act DetailsForced label of "Warning: The Surgeon General Has Determined that Cigarette Smoking Is Dangerous to Your Health" and prohibited radio and television advertisements for cigarettes. “Public Health Smoking Act of 1969.” (n.d.) Retrieved from https://web.archive.org/web/20080305012949/http://tobaccodocuments.org:80/atc/71066088.html

Immunotherapy FDA Approval

Sep 1, 1998

Herceptin FDA Approved “Herceptin (Trastuzumab) development timeline.” (n.d.) Retrieved from http://www.gene.com/media/product-information/herceptin-development-timeline

Tobacco Master Settlement Agreement

Nov 30, 1998

46 states and District of Columbia reach agreement with 5 largest tobacco companies on advertisement and payment to states. Master Settlement Agreement “Master Settlement Agreement.” (n.d.). Retrieved from http://publichealthlawcenter.org/topics/tobacco-control/tobacco-control-litigation/master-settlement-agreement

Overdiagnosis and Overtreatment in CancerAn Opportunity for Improvement

Aug 28, 2013

Diagnosis and Overtreatment in Cancer
Controversial Recommendations on changing protocols for cancer screening. Esserman, L. J., Thompson, I. M., & Reid, B. (2013). Overdiagnosis and overtreatment in cancer: An opportunity for improvement. The Journal of the American Medical Association. 310(8), 797-798. doi:10.1001/jama.2013.108415

Combined Immunotherapy Shows Promise

Jul 2, 2015

New England Journal of Medicine Study shows a combination of two medicines stopped the advancement of skin cancer in 58% of cases in a study of 945 patients. Larkin, J., Chiarion-Sileni, V., Gonzalez, R., Grob, J. J., Cowey, C. L., Lao, C. D.,...Wolchok, J. D. (2015). Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. New England Journal of Medicine, 373, 23-34. doi: 10.1056/NEJMoa1504030

Proton Beam Therapy Shows Promise

Jan 30, 2016

Proton Beam Therapy "effective with fewer side effects" Howell, D. (2016, January 30). Proton beam cancer therapy ‘effective with fewer side effects.’ BBC News Health. Retrieved from http://www.bbc.com/news/health-35440016

Nutlins Determined to cause cancer self-destruction.

Feb 20, 2016

Scientists didn't know exactly if nutlins were causing self-destructiong of cancer cells are just suppression. It turns out that it is self-destruction. Wilson, A. (2016, February 24). Scientists discover secret to promising new cancer drug. Retrieved from http://www.wehi.edu.au/news/scientists-discover-secret-promising-new-cancer-drug

Jury awrds $72 million for talcum powder cancer connection

Feb 25, 2016

Johnson & Johnson Talcum powder lawsuit.Johnson and Johnson forced to pay $72 million to family of deceased woman in Missouri. Morran, C. (2016, February, 24). Jury awards $72 million in Johnson and Johnson talcum powder cancer lawsuit. Retrieved from http://consumerist.com/2016/02/24/jury-awards-72-million-in-johnson-johnson-talcum-powder-cancer-lawsuit/