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In 476 C.E. the last of the Roman emperors Romulus was overthrown by the Germanic leader Odoacer
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The Black Death was an epidemic of bubonic plague that killed one third of Europe's total population
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Johannes Gutenberg invented the printing press in 1440
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Raphael painted the "school of Athens"
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Shakespeare was an English poet, playwright, and actor, known as the greatest writer in the English language