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430 BCE
The Plague of Athens
The plague of Athens occurred in the city of Athens, and killed 75,000 to 100,000 people. The epidemic is thought to be the first form of the bubonic plague. -
165 BCE
Antinone Plague
The Antinone Plague occurred in the Roman Empire, and killed around 5 million people. The disease is thought to be the first cases of smallpox or measles. -
541
The Plague of Justinian
The Plague of Justinian occurred in the Eastern Roman Empire and killed approximately 25 million people. The cause of the disease of a bacteria called Yersinia Pestis. -
1347
The Black Death
The Black Death was one of the worst pandemics in history. The disease killed an estimated 450 million and 75 million people were affected. The disease spread worldwide. -
First Cholera Pandemic
Cholera is a disease that is caused by contaminated food or water. The first cholera outbreak spread through the Southeast Asia to the Middle East. The amount of deaths is still unknown. -
Third Pandemic
The pandemic was the third influenza pandemic which started in Yunman, China. The pandemic went for over five decades and caused around 15 million deaths. -
Spanish Flu
The Spanish Flu was the first influenza pandemic, which affected almost 500 million people worldwide. The illness 20 - 50 million people dead. -
Asian Flu
It was the second influenza pandemic that spread worldwide. 1 to 2 million deaths occurred and the virus spread throughout Asia and to the United States. -
Hong Kong Flu
The Hong Kong Flu was the third outbreak of the influenza virus, and killed an estimated one million people. The virus could be passed through sneezes or coughs. -
HIV/ ADIS
HIV is a virus which can lead to AIDS if it is left untreated. The first cases of HIV/ AIDS were recorded in the 1980’s. As of 2011, the illness has killed 25 million people, and affected 60 million.