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Period: 1300 BCE to
Spontaneous Generation
The belief that microorganisms and small animals such as mice, flies, and toads could be ‘born’ of nonliving matter. -
1200 BCE
Asclepius (Spontaneous Generation)
Greek physician who became known as the god of medicine. His “rod” which is the medical symbol of today is believed to be a representation of the classical method to remove the guinea worm. (Spontaneous Generation Believer) -
1500
China (Spontaneous Gen)
Chinese monks used an early vaccination method against smallpox. (Spontaneous Gen) -
Robert Hooke (Spontaneous Gen)
Discovered life was composed of small boxes he dubbed “cells” by using a rudimentary microscope. -
Francesco Redi (Biogenesis)
Set up an experiment to disprove Spontaneous Generation with flies and three jars. One was open. Another was completely sealed. The last was covered with gauze. -
Period: to
Anton van Leeuwenhoek (Spontaneous Gen)
Observed the first living microorganisms and recorded detailed drawings. -
John Needham (Spontaneous Gen)
Strengthened belief in spontaneous generation with his experiment involving flasks with broth that grew microbes. -
Edward Jenner (Spontaneous Gen)
Helped develop the process of vaccination through his tests to immunize smallpox by using cow pox, a similar but weaker virus. -
Agastino Bassi (Spontaneous Gen)
Showed that a silkworm disease was caused by a protozoan. -
Period: to
Matthias Schlieden, Theodore Schwann, and Rudoplh Virchow (Biogenesis)
Proposed cell theory. (Biogenesis) -
Ignaz Semmelweis (Biogenesis)
Demonstrated that unwashed hands of physicians helped spread disease. -
Louis Pasteur (Biogenesis)
Discovered the source of Fermentation was anerobic bacteria. -
Period: to
The First Golden Age of Microbiology
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Rudolf Virchow (Biogenesis)
Developed the hypothesis that was later proven correct which stated that living cells can only come from other living cells. -
Louis Pasteur (Biogenesis)
Using a Swan neck flask experiment he proved spontaneous generation false. -
Louis Pasteur (Biogenesis)
Developed the process of pasteurization which is used for the longevity of beer, milk, etc.. -
Louis Pasteur (Biogenesis)
Found that a protozoan caused another silkworm disease. -
Period: to
Gregor Mendel (Biogenesis)
Conducted his famous pea plant experiments that established a bases for modern genetics. Source: https://www1.villanova.edu/villanova/president/university_events/mendelmedal/aboutmendel.html -
Joseph Lister (Biogenesis)
First to use phenol solution on surgical wounds to decrease infection and death during/ after surgery. -
Robert Koch (Biogenesis)
First to publicly prove that bacteria caused disease with his anthrax experiments. -
Petri (Biogenesis)
Petri Dish -
Demitri Iwanowski (Biogenesis)
Found that a disease-causing organism harming tobacco was so small it could pass through filters known to catch the smallest bacteria. Later this disease was name tobacco mosaic virus (TMV). -
Paul Ehrlich (Biogenesis)
Made the first revolutionary step in chemotherapy with Salvarsan, a arsenic derivative, chemotherapeutic agent effective against syphilis. -
Alexander Fleming (Biogenesis)
Accidently discovered the first antibiotic, Penicillin, from the fungus Penicillin chrysogenum. -
1930s
Several other synthetic drugs were discovered (E.g. Sulfonamide antimicrobial) -
Rebecca Lancefield (Biogenesis)
Set a new standard for classification with her discovery of differences in chemical composition of cell walls. -
Wendell Stanley (Biogenesis)
Demonstrated that TMV was not a bacterium but a virus. -
Chain and Florey (Biogenesis)
Isolated and raised awareness of Penicillin. -
George W. Beadle and Edward L. Tateum (Biogenesis)
“Demonstrated the relationship between genes and enzymes.” From the textbook -
Oswald Avery, Colin McLeod, and Maclyn McCarty
Established that DNA was the source of inheritance/ hereditary. (Biogenesis) -
Period: to
Second Golden Age of Microbiology
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James Watson and Francis Crick (Biogenesis)
Introduced the double helix model of DNA. -
1960
Interferons were discovered. -
Paul Berg (Biogenesis)
Was the first to produce Recombinant DNA, human or animal DNA introduced into bacteria. -
Francois Jacob and Jacques Monod (Biogenesis)
Discovered RNA. -
Sanger and Gilbert (Biogenesis)
Developed the technique for sequencing DNA. -
Period: to
Third Golden Age of Microbiology
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Source for all events