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Karl Landsteiner discovers the existence of different human blood types
The Deliverable was the blood type also called as Blood group was first found by Karl Landsteiner.It was the first ever in history that someone has discover the different existence for type of blood. He successfully found there are three types of blood groups name like A, B and O which he labeled as C blood type.
Fixed:Quality
Optimized: time
Accepted:Cost
[https://www.walkinlab.com] -
First vaccine for yellow fever
The deliverable was the first yellow fever vaccine which was found by Max Theiler.This vaccine is known as stem 17D. It was the first time ever that someone had developed the vaccination against Yellow fever while it was spreading all over the world in 1935.He had first tested first vaccination on mice which is known as “mouse protection test” and then applied it to human.
Fixed:Quality
Optimised:Cost
Accepted:Time
[http://www.800aspirin.com] -
First Heart Surgery. Where heart was stopped and restarted
The deliverable was the First successful heart surgery, where heart was Stopped and restarted. Deliverable was to give a healthy heart to the patient who was born with hole in a heart. It was done by Dr. Walton Lillehei and Dr. John Lewis.
Fix: Quality
Optimize: Time
Accept: Cost
[https://www.pbs.org/wgbh/nova/article/pioneers-heart-surgery] -
First successful pancreas transplant
Deliverable was first successful pancreas transplant. It was done to cure type 1 diabetes. It was done by Dr. W Kelly and R. Lillihei. It left patient insulin free for 6 days.
Fix: Quality
Optimize: Time
Accept: Cost
[https://www.elsevier.es/en-revista-cirugia-espanola-english-edition--436-articulo-pancreas-transplantation-50-years-experience-S2173507717300984] -
First vaccine developed for hepatitis B
The Deliverable was the vaccine for hepatitis B,which was developed by Drs. Blumberg and Millman. It was the First Commercial Hepatitis B Vaccine manufactured by Merck Pharmaceuticals.It was the first successful vaccine approved by the U.S food and drug administration (FDA) against hepatitis B In 1981.The project was temporary because,this vaccine was discontinued in 1990 and no longer available in the U.S.
https://www.asianscientist.com/2017/02/pharma/india-cipla-hepatitis-vaccine/ -
HIV
The deliverable was the finding of Human immuno deficiency virus(HIV).Research groups led by Dr. Gallo, Dr. Luc Montagnier at the Paris Pasteur Institute, and Dr. Jay Levy at the University of California, San Francisco, reported that a retrovirus was the cause of AIDS in 1984.It is temporary because,after the successful invention of the virus there is no need for further research.
https://www.avert.org/professionals/hiv-science/overview -
Dolly the Sheep: first mammal cloned from an adult somatic cell
The project deliverable was Dolly: the first cloned individual, and thus unique. It was planned/executed by Roslin Institute, Edinburgh University. It was temporary and completed in 1996 when Dolly was born. Quality fixed: the project was only successful if the single cell “lived” .Price optimised: the project was funded by PPL Therapeutics/ Ministry of Agriculture.Time accepted: whilst the team wanted to be first, they were not under time pressure to complete.[https://www.britannica.com/] -
The Human Genome Project (HGP): the project purpose was to deliver the first draft of human DNA sequencing
HGP: a collaboration of the US federal government/Private program. It had a time-frame so was temporary, and the deliverable was the first draft of the human genome. Unique, as had never previously been achieved. Quality fixed: an accurate draft was essential. Time optimised: limit of 15 years, but success of HGP meant it is likely it would have been extended. Cost accepted: US$3.8B spent but economic impact of the HGP estimated over US$796B. [https://christiannewsjournal.com]
