-
Discovery
Fredrick Banting discovered Insulin extract from pancreas of dog. -
Human Contact
Banting and Best give insulin to a person for the first time. -
Purified Insulin
Injections developed by Collip were given to patients. -
Commercially Produced
There was a shortage so insulin was made commercially and was given out in portions of 5-18 ml and was meant to be taken twice a day. -
Crystalized Insulin
Abel was able to crystalize insulin into 51 amino acids. -
Protamine zinc
First made. -
Lente Insulin
First made -
Small Measures
Minute concentrations can be consistently measured. -
recombinant Insulin
The first recombinant "human" insulin is produced by Beckman Research Institute and Genentech. -
Insulin Lispro
Dr. Weiss and colleagues describe the structure of derivatives of insulin lispro (the active component of Humalog) in solution. -
Hormone- binding site
Dr. Weiss and colleagues in an international team describe for the first time how insulin engages the primary hormone-binding site in the insulin receptor. -
Rapid acting insulin
Thermalin prepares for the first clinical trial of Fluorolog™, the first highly concentrated, rapid-acting insulin.