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De Bordeu, Theophile presented the ideal of organs, tissue, and cell discharges influence other body part of the body.
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Bernard, Claude (1813-1878), Claude Bernard invented the term ‘internal secretion’, showing that the body can both break down and build up, complex chemical substances.
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Adrenaline was the first hormone to be isolated.
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Takamine, Jokichi (1854-1922).Isolation of adrenaline in crystalline form from the adrenal medulla.The blood-pressure-raising principle of the suprarenal glands.
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Pavlov developed a theory of nerve regulation of salivary and alimentary glands. He included the regulation of the pancreas in his theory.
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Ernest Starling and William Bayliss isolated secretin, the first substance to be called a hormone.
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Bayliss and Starling developed the theory of hormonal control of internal secretion.
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1910
Biedl, Artur (1869-1933), Biedl showed that the adrenal cortex is essential for life. His classic work shows the rapid development of the knowledge of endocrinology. -
Kendall, Edward C isolated and crystallized the active principle of the thyroid, named thyroxin. In 1949, he discovered that cortisone could relieve symptoms of rheumatoid arthritis.
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1915
Cannon, Walter Bradford (1871-1945), Cannon showed the close connection between the endocrine glands and the emotions. -
Human growth hormone is discovered by Evans and Long.
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Banting, Frederick & Mcleod, JJ & Best, Charles, The Canadians Banting, McLeod and Best succeeded in lowering the level of blood-sugar when they used insulin to control the carbohydrate metabolism.
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Medical student Charles Best, discovered insulin