Early Embryonic Development

  • Jan 1, 1111

    Day 1: Fertilization

    Day 1: Fertilization
    The sperm fertilizes the egg to form a zygote in the falopian tube; begins 1st trimester
  • Jan 1, 1112

    Day 1: Cleavage

    Day 1: Cleavage
    A mitotic cell division occurs in the zygote multiple times as the zygote becomes a pre-embryo and develops into a multicelular blastocyst; eventually ends when uterine wall is contracted
  • Jan 1, 1113

    Day 2: Morula

    Day 2: Morula
    A solid ball of blastomere cells forms from cleavage phase; reaches uterus on 4th day
  • Jan 1, 1114

    Day 5: Blastocyst/blastocoele

    Day 5: Blastocyst/blastocoele
    The morula develops inner cavities and an inner cell mass; formed by many blastomeres as division continues
  • Jan 1, 1115

    Day 7: Implantation

    Day 7: Implantation
    The blastocyst adheres to the uterine lining as the trophoblast cells rapidly divide to create several layers
  • Jan 1, 1116

    Day 16: Gastrulation

    Day 16: Gastrulation
    The 3rd layer of cells begin to form (mesoderm) as others move towards the central line; the primitive streak begins to form
  • Jan 1, 1117

    Day 18: neural neurogenesis

    Day 18: neural neurogenesis
    The neural grooves and folds of the developing brain are first seen
  • Jan 1, 1118

    Day 20: Musculoskeletal somitogenesis

    Day 20: Musculoskeletal somitogenesis
    1-3 somite pairs appear in the neural groove and can now be added to sequence to develop the musculoskeletal system in the embryo
  • Jan 1, 1118

    Days 21-25: Organ generation and development continues

    Days 21-25: Organ generation and development continues
    Heart cardiogenesis occurs on day 21 as paired tubes; laryngotracheal groove (precursor to lungs) forms on day 22 to begin respiratory development; Thyroid development begins on day 24; Liver formation begins on day 25
  • Jan 1, 1118

    Day 27: Beginning of Vascular Dev.

    Day 27: Beginning of Vascular Dev.
    The hindbrain is supplied by 2 arteries to begin the development of the circulatory system and bloodflow
  • Jan 1, 1119

    Day 31: Sense Appearance and Visibility of Organs

    Day 31: Sense Appearance and Visibility of Organs
    Sensory receptors and sight and smell structures become prominent in the embryo while the 4th brain ventricle also appears; The heart, liver, and umbilical cord become externally visible as bulges protruding from the embryo
  • Jan 1, 1120

    Days 35-36: Further Organ Development

    Days 35-36: Further Organ Development
    The pituitary gland becomes defined and independent in the proper location; Parathyroid glands generate in the thyroid; Adrenal glands begin to form; Heart and lungs descend into thorax; tongue begins to become defined
  • Jan 1, 1121

    Day 41: Sense Organs Distinguish Structure

    Day 41: Sense Organs Distinguish Structure
    Olfactory nerve fibers enter the brain to provide the early parts of the smell sense; Eyelid sulcus deepen as eyelid folds develop
  • Jan 1, 1123

    Day 43: Middle Organs Perform Important Roles

    Day 43: Middle Organs Perform Important Roles
    The pancreas secretes insulin at an increasing rate; Liver enlargement stops the movement of the heart and lungs, keeping them at the desired location
  • Jan 1, 1125

    Days 51-52: Structure and Digestion Established

    Days 51-52: Structure and Digestion Established
    The abdominal cavity becomes defined to provide structure with the presence of muscle arising along with connective tissue presence; The gastrointestinal tract seperates from the anal membrane
  • Jan 1, 1126

    Day 55: Sex Hormone Secretion Begins

    Day 55: Sex Hormone Secretion Begins
    Testosterone production begins in the embryo
  • Jan 1, 1127

    Day 56: End of Embryonic Development and Beginning of Fetal Phase

    Day 56: End of Embryonic Development and Beginning of Fetal Phase
    Body trunk straightens; Rounded head; Abdominal wall forms 3 layers; G cells in stomach begin to appear; Fetal development begins