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First Compound Microscope
hans and Zacharias Janssen, constructed the frist compound microscope using two lenses inside a tube -
Robert Hooke's Develoment of the Microscope
First saw cells in a slice of cork and named them cells -
Animalcules
Unicellular organisms were discovered by Anton Van Leeuwenhoek and called them 'animalcules' -
Leeuwenhoek discovers bacteria
Leeuwenhoek discovers bacteria from saliva -
Rene Dutrochet
Rene Dutrochet stated all animals and plants were made of cells -
Robert Brown discover the nucleus
Robert Brown discover the nucleus inside orchid cells -
Cell Theory Formulated
Matthias Schleiden and Theodor Schwann formulated the cell theory; that all living matter is composed of cells -
Pre-Existing Cells
Rudolf Virchow stated that 'where a cell exists there must have been a pre-existing cell. just as the animal arises only from an animal and the plant only from a plant' -
Cell Division (mitosis)
Walther Flemming described cell division (mitosis) from observations of living and stained cells -
Electron Microscope
Ernst Ruska built the first electron microscope. Details of internal cell structures were revealed. -
X-Ray/DNA
An image of crystaline DNA helped James Watson and Francis Crick to reveal the structure of DNA. -
Confocal Microscope
Marvin Minsky developed the first confocal microscope which was able to produce 3D images of cells and cell structures. -
Two-Photon Fluorescence Microscope
Two-Photon Fluorescence Microscope was developed by Winfried Denk which uses laser light that creates 3D images within tissues without damaging cells.