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O'Brien was born in St. Paul, Minnesota,
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She was educated at Williams College, and earned her MA at Johns Hopkins University.
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After college she began teaching high school students but then wanted to focus on writing so she left teaching to begin writing romance novels
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In 2010 she published her first novel called Birthmarked
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Birthmarked, was a Junior Library Guild selection and an American Library Association Best Book for Young Adults, and was nominated for the YALSA Best Fiction for Young Adults list as well as the 2010 Amelia Bloomer list.
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She continued on and made the birthmarked a trilogy and has now publshed 5 novels
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Caragh is now a succusseful continued novelist for teens