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527
Justinian became the leader of Byzantine empire
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532
The Hagia Sophia was destroyed, Byzantine empire rebuilt it.
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542
The worst year of the Plague, 10,000 people were dying everyday
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565
Justinian died, the Byzantine empire rebuilt itself.
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Feb 25, 626
the persians and avars struck against constantinople itself.
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Mar 25, 1043
russians attempted invasions, the turls took over the muslim world and fought their way into the Byzantine empire
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Jun 16, 1453
constantinople finally fell to the ottoman turks
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Justinian's wife died and afterwards he was so depressed he passed no more major laws