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Period: 542 to 750
Plague of Justine
During the reign of the emperor Justinian I, one of the worst outbreaks of the plague took place, claiming the lives of millions of people. The plague arrived in Constantinople in 542 CE, The outbreak continued to sweep throughout the Mediterranean world for another 225 years, finally disappearing in 750 CE. -
Period: 1347 to 1353
Bubonic plague
In the Late Middle Ages Europe experienced the deadliest disease outbreak in history when the Black Death, the infamous pandemic of bubonic plague, hit in 1347, killing a third of the European human population. -
Period: to
Spanish Flu
The Spanish flu, also known as the 1918 flu pandemic, was an unusually deadly influenza pandemic caused by the H1N1 influenza A virus. Lasting from February 1918 to April 1920. -
COVID-19
The detection of an outbreak of pneumonia caused by an unknown pathogen in Wuhan, China, in December 2019 began the start of a cataclysm that has swept the world. Events have moved with astonishing speed. The same day that a rapid response team was sent to Wuhan from the Chinese Centre for Disease Control and Prevention in Beijing to assist local health authorities investigate the outbreak.