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541 BCE
The Plague of Justinian -541 A.D.
The plague of Justinian started in 541 A.D. in the Middle East, Asia, and the Mediterranean Basin. It went on and off for nearly 200 years and killed over 50 million people. -
430 BCE
Smallpox-430 B.C.
Smallpox killed more than 30,00 people in Athens, Greece. This was caused by the Variola virus and reduced the population by at least 20%. The virus was transmitted through skin to skin contact, bodily fluids, and the air. -
429 BCE
The Plague of Athens -429 B.C.
The plague of Athens started in Greece throughout 429-426 B.C. The plague killed 75,000-100,000 and the disease is unknown but it is thought to be Typhus. -
165
Antonine Plague -165
The Antonine plague started on 165 and ended around 180. It affected Europe, Western Asia, and Northern Africa and killed 5 million people, reducing the population by 30% in some areas. -
540
Bubonic Plague -540
The bubonic plague started in the 540s in Europe, Africa, and Asia. The bubonic plague was so violent that people thought it was a punishment for their sins. 10,000 people died daily because of this plague. -
1334
Great Plague of London -1334
The great plague of London started in China and spread along the trade routes. It ended up harshly affecting Florence, Italy which lost 1/3 of it's 90,000 residents in the first 6 months. -
1346
Black Death -1346
The black death started in 1346 and ended around 1350. It killed 75-200 million, reducing the population of Europe, Asia, and North Africa by 30-60%. -
1519
Smallpox -1519
Smallpox was brought in when Hernando Cortes arrived at Mexico in 1519. The disease killed 5-8 million of the native population in 2 years. -
1545
Cocoliztli -1545
The disease that caused Cocoliztli was Viral Hemorrhagie fever. This affected Mexico where it reduced 80% of the population (5-15 million dead). -
Italian Plague -1629
The Italian plague originated in Italy which is where it got its name from. In Italy, it killed about 280,000 people. -
Smallpox -1633
The disease reached Massachusetts in 1633 which was brought by settlers from France, Great Britain, and the Netherlands. It was estimated that there were 20 million dead. -
Russian Plague -1770
The Russian plague started in Russia in 1770-1772. In Russia, it killed more than 50,000 people. -
Yellow Fever -1793
The Yellow fever pandemic started in Philadelphia in 1793. In Philadelphia, it killed 45,000 people, reducing the population by 1/10th. -
Second Cholera Pandemic -1829
The Second Cholera pandemic lasted almost 20 years when it started in 1829. It affected Europe, Asia, and North America. More than 100,000 people died. -
Typhus Epidemic -1847
The Typhus epidemic started in Canada on 1847. It lasted a whole year and more than 20,000 people died. -
Modern Plague -1860
The modern plague originated in China, India, and Hong Kong. It killed more than 12 million people until, in 1890, people figured out how it was spread and a vaccine was created. -
Flu Pandemic -1889
The Flu pandemic lasted 1 year. It was caused by the influenza virus and it killed 1,000,000 people worldwide. -
Third Plague Pandemic -1900
This was caused by the Bubonic plague and it lasted 4 years. It affected mainly San Francisco where 113 people died. -
Smallpox -1901
Smallpox started in Boston in 1901. In Boston, 1,500 people were infected but only 270 deaths were reported. -
Plague -1910
This was the largest plague outbreak in the 20th century. It started in Manchuria between 1910 and 1911 and it killed 60,000 people. -
Great Flu pandemic -1918
The Great flu pandemic was caused by the influenza virus. It started in 1918 and ended around 1919. It killed between 30 million and 50 million, 675,000 Americans died. -
HIV/AIDS Pandemic -1960
This pandemic started in the 1960s and it still continues now. It started in Congo Basin and it has killed over 30,000,000 people. -
SARS -2002
SARS was caused by a disease called SARS coronavirus. It started in Asia and Canada where 775 died in total. -
Ebola -2013
Ebola started in 2013 and ended around 2016. Is originated in West Africa but there was a reported case in the United States. More than 11,300 people died.
