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Tomas Farynor forgot to put out the fair in one of his ovens.
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The spark set fire to the straw of the bakery. Flames began to spread.
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London's mayor, Sir Thomas Bloodworth, was advised to have all the neighbouring houses demolished, as this would stop the fire spreading, but the mayor refused to give the order.
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Three hundred houses were on fire and winds from the east were causing the fire to spread with frightening speed.
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Winds finally died down, to bring the fire under control.
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Fire was totally extinguished.