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1333
Plague breaks out in north eastern China, killing 5 million people in that year.
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1339
Nestorian Christian community in Central Asia wiped out.
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1346
Plague reaches Crimea. Genoan merchants return to Sicily spreading the disease.
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1347
Plague spreads rapidly to Cyprus and then into modern day Italy, reaching Venice as well as Alexandria in Egypt.
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1348
Plague reaches Paris, Marseilles and then England. Moves along the Rhine River into modern day Belgium, Netherlands & Luxembourg. Outbreaks occur in Cairo and Gaza leading to serious persecution of the Jews.
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1349
Widespread persecution of Jews, with thousands burned to death. Plague reaches Aswan in Egypt and the entire Islamic world is now affected.
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1350
Plague has largely run its course in the Mediterranean basin.
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1351
Plague reaches Russia.
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1357
35 million deaths from the plague are recorded since 1333.