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Wilhelm Kolff
Wilhelm Kolff is born in Leiden, Netherlands. He would go on to produce some of the first artificial hearts for Kolff Medical.
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Period: to
The Artificial Heart
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Leiden University
Wilhelm Kolff begins medical study and earns his degree in 1937 http://www.syncardia.com/artificial-heart-timeline/timeline/itemid-1646.html -
Heart-Lung machines
WIlhelm Kolff begins to work on artificial hearts and heart lung machines.
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First Test
Dr. Kolff tests his first artificial heart on a dog, it lives for about 90 minutes.
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Paul Winchell
Paul Winchell is granted the first patent for an artificial heart, which he later signs over to Dr. Kolff
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First human
The first doctor to transplant a humans heart with an artificial one was Dr. Denton Cooley, the patient survives on the artificial heart but dies 32 hours after having an actual heart transplant.
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Cow Test
A calf survives for 268 days on the Jarvik 5 Artificial heart, Dr. Kolff sends a request to the FDA to implant the heart into humans.
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Successful Transplant
The Jarvik 7 Artificial heart is implanted into Dr. Barney Clark, he lives for 112 days. http://emedicine.medscape.com/article/2052514-overview -
Another Success
Will Schroeder becomes the second human to recieve a Jarvik 7 artificial heart, he survives on it for 620 days, the longest time survived up to this point.
http://www.nytimes.com/1986/08/07/obituaries/william-schroeder-dies-620-days-after-receiving-artificial-heart.html -
FDA
The FDA shuts down Kolff Medical, now Symbion Inc., due to violations of FDA guidelines. A new company, CardioWest Tech, is sent the Jarvik 7 technology and begins further
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30 years later
The 125th transplant of the Total Artificial Heart is a success.
