Prenatal Brain Development

  • Month 1

    Month 1
    1. By the end of the first month of pregnancy, your baby is around 6-7mm (1/4 inch) long - about the size of a grain of rice.
    2. The amniotic sac is a water-tight sac that forms around the fertilized egg. It helps cushion the growing embryo throughout pregnancy.
  • Month 2

    Month 2
    1. The baby is now a little over half an inch in size. Eyelids and ears are forming, and you can see the tip of the nose. The arms and legs are well formed. The fingers and toes grow longer and more distinct.
    2. The neural tube (brain, spinal cord, and other neural tissue of the central nervous system) is well formed. The digestive tract and sensory organs begin to develop. Bone starts to replace cartilage. The embryo begins to move, although the mother cannot yet feel it.
  • month 4

    month 4
    1. Some symptoms of brain damage may not be evident until the child starts attempting to undergo developmental milestones. The symptoms of brain damage are calculated in a few different ways: cognitive, perceptual, physical, and behavioral or emotional.
    2. The symptoms of brain damage are calculated in a few different ways: cognitive, perceptual, physical, and behavioral or emotional.
  • month 5

    month 5
    1. The study of the development of the human brain while in utero, was to conduct these studies through Ultrasonography this method had limitations in conditions such as maternal obesity, in turn.
    2. However, MR in the fetus is also challenging due to fetal motion and position, and that is why the RARE technique has been applied). As stated in the article, this technique allows us to detect abnormalities in the central nervous system.
  • month 6

    month 6
    1. Given that the fully developed cortex has a total of six layers, this finding showed that at this gestational age, the cerebral cortex was not at its full term, indicating that in regards to the brain’s inside out development process, other brain structures were also in the process of reaching maturity 2.From 24 to 26 weeks, only a few shallow grooves were seen in the central sulcus and three layers of the cerebral cortex were differentiated.
  • month 7

    month 7
    1.By 30-32 weeks of gestational age, deep sulcation was seen in the whole cerebral cortex , however, it had not undergone infolding; a process which was observed to appear from 33 weeks and on.
    2.By the 36th week, the cortex was extensively and compactly folded, depicting the advancement in cortical maturation.
  • month 8

    month 8
    1. In regards to the cerebral ventricles, they appeared to be large up until the 23rd week, and after that, they gradually became smaller in size.
    2. In turn supporting the idea that while in the womb, the fetus in regards to its stage based process of brain development is undergoing a period of great vulnerability that if tampered with, may result in long lasting detrimental consequences.
  • month 9

    month 9
    1. Lying beneath the cortical plate, the Sub Plate (SP) forms transient circuits with thalamo and cortico-cortical axons, pausing in their axonal projection to the Cortical Plate. 2.The time course of development of the sub plate is organized into sections, the first being the “pre-sub plate stage” which happens at 10-12 weeks post conception, the next is referred to as the “sub plate formation stage.¨
  • Month 3

    Month 3
    1. Cognitive symptoms are usually identified as the child grows older and possibly misses normal developmental steps.
    2. The most common symptoms include difficulties with Attention and concentration Memory and processing information Processing language Controlling impulses Communication