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1492
First voyage of Christopher Columbus to the western hemisphere
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1494
Treaty of Tordesillas
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1500
Brazil claimed for Portugal by Pedro Alvarez de Cabral
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1518
Smallpox epidemic in the Caribbean
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Period: 1519 to 1521
Spanish conquest of Mexico
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1525
Execution of Cuauhtemoc
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Period: 1532 to 1540
Spanish conquest of Peru
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1545
Spanish discovery of silver near Potosi
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Foundation of Port Royal (Nova Scotia)
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Foundation of Jamestown
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Foundation of Quebec
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Foundation of New Amsterdam
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Foundation of the Massachusetts Bay Colony
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Smallpox epidemic on Guam
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Period: to
French and Indian War in North America
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Transfer of French Canadian possessions to British rule
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Period: to
Captain James Cook's exploration of the Pacific Ocean
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Establishment of first European colony in Australia