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Period: 165 to 180
Antonine Plague (Pandemic)
The Antonine Plague is one of the earliest pandemics in the world. It started in China and Rome. Its symptoms are fever, diarrhea, and pharyngitis as well as a skin eruption. It started in 165CE and ended in 180CE. -
Period: 541 to 542
Plague of Justinian (Pandemic)
The plague of Justinian was the first plague in the world. The plague may have originated in China or India and was then transported to the fertile valleys of Egypt through trade routes, then to other parts of the world. The symptoms of the plague of Justinian are fever, headache, chills, swollen or tender lymph nodes, abdominal pain, gangrene. It started in 541 and ended in 542. -
Period: 627 to 628
Plague of Sheroe (Epidemic)
The plague of Sheroe was a plague which started in Iran and spreaded in that area. The symptoms of the plague of Sheroe was fever, headache, chills, and weakness and one or more swollen, tender and painful lymph nodes (called buboes). This form usually results from the bite of an infected flea. This plague started in 627 and ended in 628. -
Period: 1346 to 1353
The Black Death (Pandemic)
The Black death pandemic started in China to Europe and all parts of the world. Its symptoms were Fever and chills, extreme weakness, abdominal pain, diarrhea and vomiting, bleeding from your mouth, nose or rectum, or under your skin, shock, blackening and death of tissue in your extremities, most commonly your fingers, toes and nose. This disease started in 1346 and ended in 1353. -
Period: 1520 to
Smallpox (Epidemic)
Smallpox started in 1520. The symptoms of smallpox includes high fever, fatigue, a headache, and a backache. After 2 to 3 days of illness, a flat, red rash appears. It usually starts on the face and upper arms, and then it spreads all over your body. It ended in 1980. -
Period: 1545 to 1580
Cocolitzi (Epidemic)
Cocolitzi was a disease which started in southern and central Mexico Highlands, near modern-day Puebla City. Its symptoms are high fever, severe headache, vertigo, black tongue, dark urine, dysentery, severe abdominal and chest pain, head and neck nodules, neurologic disorders, jaundice, and profuse bleeding from the nose, eyes, etc. It started in 1545-1548 and 1576-1580. -
Period: to
Cholera Disease (Pandemic)
Cholera was a disease which started in India to all parts of the world. It was caused by A bacterium called Vibrio cholerae. The symptoms of Cholera are vomiting, thirst, leg cramps, watery diarrhea, restlessness or irritibility. Cholera started in 1817 and ended in 1851. -
Period: to
Spanish Flu/Influenza (Pandemic)
Spanish Flu was one of the most severe pandemics in the world. It was caused by an H1N1 virus with genes of avian origin. The symptoms of the Spanish flu were chills, fever and fatigue. The Spanish flu started in 1918 and ended in 1919. -
Period: to
World War 1 Typhus (Epidemic)
Typhus was a disease that was caused by bacteria. Its symtoms are severe back pain, joint pain, headache, tummy pain, diarrhoea, very high temperature, etc. This disease was spread in soviet regions. -
Period: to
Ebola Disease (Epidemic)
Ebola is a disease which is caused by monkeys, apes, chimpanzees, etc. Ebola started near the Ebola river which is now called the Democratic Cepublic of Congo. The symptoms of Ebola are fever, aches and pains, such as severe headache, muscle and joint pain, and abdominal (stomach) pain, weakness and fatigue, gastrointestinal symptoms including diarrhea and vomiting, abdominal (stomach) pain. Ebola started in 2014 and ended in 2016. It also started in 1976.