-
430 BCE
Plague of Athens
100,000 deaths -
165
Plague of Antonine
Brought back by troops from the Middle East; 5 million deaths -
541
Plague of Justinian
Killed an estimated 100 million, half of the world's known population. -
Jan 1, 1334
Black or Bubonic Plague
Killed an estimated 75 to 200 million. -
Jan 1, 1545
Cocoliztli Plague in Mexico
15 million deaths -
1563
Plagues of London
Killed 100,000, a fifth of London's population. 1563, 1592, 1603, and the Great Plague of 1665 -
Plague of South America
Malaria (no figures on deaths)