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Abnormal behavior was once thought to be caused by demonic possession, only to be cured by excursion. Therefore, the cure was to have patients' heads drilled to release the demons.
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Over 600 impoverish black sharecroppers were studied by the U.S. Public Health Service to document disease in blacks, and racial differences in the clinical manifestations of syphilis. The men were not told they had syphilis or given concealing on how to stop the spread of the disease.
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Electrical shocks were applied to animals without attention. When yale psychologist Stanley Milgram applied shocks to human participants the world became outraged.
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Researcher Laud Humphreys pretended to be a member of a homosexual community to observe their behavior in public places. The study was criticized since Humphrey did not get his subjects' consent nor identify as a researcher.
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A mock prison was set up so participants could experience their roles which was either a guard or a prisoner. With the prisoners experiencing everything from arrest to strip searching, the study showed how reasonable people could become unreasonable, referring to the guards.