-
Period: to
Leeuwenhoek
Observed yeast cells in fermentation sediments -
Period: to
Lavoisier
Sacharose --- (sediment)----> ethanol+CO2 -
Period: to
Theodor Schawn
suggested yeast promoted the fermentation process, whose growth was due to sugar consumption and conversion. -
Period: to
Louis Pasteur
He thought it was imposible the fermentation without the simultaneous organization, development and multiplication of the globules or, at least, those present continue to be alive. -
Period: to
Eduard Buchner
Live cells are not essential in the fermentation process
1897: Beginning of modern biochemistry -
Period: to
Wilhelm Kühne
Coined the term enzyme (in the yeast in greek) -
Period: to
Meyerhof
Principle of universality of the metabolism
LDH -
Period: to
Purification and nature of the enzymes
1920: Sumner vs Willstäeter
1930: Sumner and Northrop Nobel Prize 1946 -
Period: to
High specificity of enzymes
1936: Keilin and Mann-----> peroxidase
Chance
1964: Kunio Yagi------> D-amino acid oxidase -
Period: to
Cory and Gerty Theresa
Isolated F1P and PP in liver
Nobel Prize 1947 -
Period: to
Severo Ochoa (Madrid)
3 ATP/O -
Period: to
Lipmann and Hans Krebs
ATP
Nobel 1953 shared with Krebs -
Period: to
Peter Mitchell
Chemoosmotic coupling
Nobel 1978