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People that acted abnormally were thought to be possessed by demons. The "medicine man" drilled holes in peoples' heads to let the demons out.
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Terrible experiments were conducted on those considered "impure". They were tortured and murdered for no reason.
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A set of ethics codes that have to be followed if using human participants to conduct research.
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Stanley Milgram using electric shock on humans
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The health insurance portability and accountability act established the conditions under which protected health information may be used or disclosed by covered entities for research purposes.