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476
The last Roman emperor in the West, Romulus Augustus, was deposed by the Foederati Chieftain, Odoacer.
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532
Justinian I orders the construction of the Hagia Sophia.
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540
The Ostrogoths convinvce the Persians to break their "Eternal" peace agreement with the Byzantine Empire. This creates a four front war for the Byzantines: Italy in the West, Persia in the East, Moors in North Africa and Barbarian tribes in the Balkans.
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552
Justinian receives silkwormm eggs smuggled from China by two Nestorian Monks. He intends to set up his own Silk production to bypass the need to trade with the far East.
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572
Byzantine Emperor Justin II breaks peace with Persia and invades Nisibis. Lombards take the Byzantine stronghold of Pavia and establish the Kingdom of the Lombards in Northern Italy.
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Feb 12, 600
Smallpox arrives in Europe for the first time. Augustine of Canterbury converts King Ethelbert of Kent to Christianity.
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Feb 12, 610
Heraclius overthrows the Byzantine Emperor and changes the official language from Latin to Greek. The Avars attempt and fail to invade Italy.
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Clovis I becomes ruler of the Salian Franks at the age of 13 after the death of his father.
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Cerdic and Cynric land somewhere on the south coast of Great Britain.
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Cerdic becomes the first King of Wessex.
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Constantine of Kernyw converts to Christianity. Dumnonia is the Southwestern most peninsula of Britain.
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The Byzantines push back the Slavs, Avars, and Gepids and cross the Danube into Wallachia.