Ancient America and The Age of Exploration By Tyson R. 2600 BCE The Mayan civilization starts 1200 BCE Olmec civilization develops 1150 Ancestral Pueblo peoples live in large complexes of stone dwellings in Ancient Southwestern America 1200 The Inca settle in the Cuzco Valley 1325 Aztecs found the city of Tenochtitlan and begin to gain power in Mesoamerica 1400 Portuguese explore the coast of Africa 1492 Columbus reaches the Caribbean 1520 Spanish conquer Aztec and Inca empires in South America and Mesoamerica 1522 Magellan's expositions around the world circumnavigates the globe 1533 The Inca empire falls to Spanish invaders in South America 1607 English colonists found Jamestown 1619 First enslaved Africans arrive in Virginia