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The First extraction of Insulin
Frederick G Banting manages to properly extract the first traces of insulin from canine pancreases. -
The First Purifications of Insulin
James B Collip hastily made improvements to the initial extract of insulin, making it more pure and safer to use. -
The First Human Trial
Leonard Thompson, a 14 year old boy, is successfully treated with the purified insulin extracts. He lives with T1D for another 13 years. -
Discovery of a Prolonged Insulin
Christian Hagedorn discovers that insulin's effects can be prolonged with the addition of Protamine. -
Intermediate Insulin Development
Novo Nordisk, a Danish pharmaceutical, creates an intermediate acting insulin called NPH. -
Insulin is Fully Sequenced
Insulin becomes the first protein to be fully sequenced, completed by British biochemist Frederick Sanger. He receives the Nobel Prize in 1958 for his contributions. -
Protein Synthesis
Insulin becomes the very first human protein to be fully Synthesized, making for easier production and distribution. -
Insulin Production
Insulin is the first human protein to be able to be produced by biochemistry and technology, done by company Greentech. -
"Human Insulin"
Synthetic insulin takes on a new name of "Human Insulin", making it distinct from animal insulin from years back. People have far less allergic reactions to this synthetic, human insulin. -
The Insulin Pens
Novo Nordisk creates the first insulin pen delivery system, making boluses easier and better to keep track of. -
Insulin Pumps
Medtronic releases the MiniMed Insulin Pump, which can give boluses and daily insulin totals. It's fairly large comparatively with not a lot of advanced tech behind it- yet it was still a great invention and product for its time. -
Analogue Insulin
Humalog is the first analogue insulin to be marketed. Analogue insulin is a kind of insulin which has been modified to tamper with the absorption rate and metabolism rate. -
Islet Cells
More than 470 patients with type one diabetes are treated with an Islet cell transplantation. With immunosuppresant drugs, they are able to live a life with little to no diabetic complications. -
"Artificial Pancreas"
Pairing the technology of a CGM and an Insulin pump, Cambridge University creates an artificial pancreas. -
"Bridge to a Cure"
Created by Dr. Edward Damiano, the iLet is created. The iLet is another form of artificial pancreas, where it will give both insulin and glucose as needed.