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Ptolemy put his theory up that the earth was in the center of the universe.
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On his death bed, Copernicus published his book about his theory that the sun was in the center of the universe.
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"On the Fabric of the Human Body" is about the human body and how it functions, it was published in 1543.
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Galileo's experiment showed that the mass of an object doesn't effect the speed of when it falls.
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Francis Bacon published the book in 1605, the book was about scientific knowledge.
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Johannes Kepler published his Laws of Planetary motion in 1604, based off of Tycho Brahe's observations.
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In 1665, Robert Hooke discovered cells under a microscope, and named the cell himself.
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In 1676, Antonie van Leeuwenhoek bacteria as he was observing his water.