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5000 BCE
Before 4000 BCE
Nomadic tribes - no spread of germs beyond their community -
Period: 5000 BCE to 4000 BCE
Nomads
Nomadic Tribes -
4000 BCE
Agriculture- Settlements begin
Settlements begin to arise alongside agriculture.
Living closely and in mostly unsanitary conditions alongside animals, zoonotic diseases spread faster and easier -
Period: 4000 BCE to
Sedentary lifestyle
Utilization of agriculture - Cities, towns, etc -
542 BCE
Plague of Justinian - Byzantine empire
During 541 and 542 BCE, in the byzantine empire, Yersinia Pestis, otherwise known as the bubonic plague, spread to humans through fleas that rats carried
This killed 25-50 million people, which was around 1/4 of Earth's population at the time -
1347
The Black Death - Sicily
The Bubonic plague returned to the shores of Sicily. Venice banned sailors for entering the city for 40 days, this is the origin of quarantine. These efforts helped deter the plague slightly, but in the end it killed 100-200 million people across 2 years, 1/3rd of the Earth's population back then. -
1521
Conquest of America - Smallpox/Viruela bioweapon
As conquerors arrived to America, they carried their ilnesses with them, and the natives having no immunity to any of them, perished great losses of around 20 million people, aiding the conquerors in their efforts to colonize. -
Spanish Flu pandemic
Across 263 days, the Spanish flu infected around 500 million people, and killed 33 million of them
By the end of 1920, it had killed about 50-100 million people, 4% of the global population.