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She was born in Galicia.
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Her mother died of smallpox
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Her son was born
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She was the rectora of the hospital of Charity in A Coruña.
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She accepted to be the nurse in the expedition which would take the smallpox vaccine to America thanks to orphaned children, including Zendal's son. The children were aged between three and nine years, and would be inoculated with the smallpox vaccine.
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Francisco Xavier Balmis, the director of the Royal Philantropic Expedition, hires her.
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The expedition sailed from the port of La Coruña on the corvette María Pita.
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Period: to Feb 9, 804
Zendal was in charge of keeping the chain of vaccination alive among the children who would carry the vaccine.
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The expedition left Acapulco to arrive to Philippines with 26 children.
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After all those years helping people with the vaccine, Isabel Zendal settled down in Puebla de los Ángeles, México.
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In 1950, the World Health Organization recognised her as the first nurse in history to take part in an international mission.