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Born
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Metchnikoff begins comparative embryological research.
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Metchnikoff
Publishes a series of papers on sponges, attacks Haekel's gastrea hypothesis and argues for parenchymella as the primordial metazoan. Turns to the problem of intracelullar digestion -
Embryological studies
Extends comparative embryological studies and embraces Darwinism -
Phagocytosis
Theory elaborated as a case of physiological inflammation beings studies of phagocyte bactericidal capacity against certain microorganisms. -
Discovery of antibacterial substance in the blood, Metchnikoff contests the humoral theory of immunity
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Metchnikoff delivers Lectures on the Comparative Pathology of Inflammation
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Metchnikoff publishes his opus magnum, Immunity in Infectious Diseases
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Nobel Prize jointly awarded to Metchnikoff and Ehrlich
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Ilya Metchnikoff dies.