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Poe was born in Boston, Massachusetts to two actors (Elizabeth and David Poe).
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Poe's mother died of Tuberculosis (shortly after Poe learned that his father also died), leaving Poe and his two siblings orphaned. They were then split up and Poe went to live with John and Frances Allan.
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This was Poe's first book.
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Poe was very close to her, which is why he was greatly affected when she died to tuberculosis.
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Poe was able to achieve this due to the help from his foster father with whom he had many quarrals in the past but they settled their disputes to honor Poe's dead foster mother's will.
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Henry also died with tuberculosis
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he stayed in Baltimore with his aunt Maria Clemm and her daughter Virginia, whom eventually he fell in love with.
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The Raven is one of his greatest works. He was writing it as his wife was dying of tuberculosis in the next room.
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The reasons for his death are unknown.