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Thomas Willis
Thomas Willis wrote a chapter describing diabetes and symptoms of the disease such as sweet urine. -
Linking of Diabetes and Pancreatic Function
Physician Oscar linked diabetes to pancreatic function through testing the effects of removing the pancreas from dogs whereby sugar appeared in the urine. -
Discovery of Insulin
A team in Toronto led by Banting and Macledd which also included Best and Collip discovered insulin as a key molecule that restored function -
Insulin used to treat a patient
Clinical application of insulin was used to treat a young boy who was dying of diabetes -
Nobel Prize Award
The Nobel Prize was awarded to Macledd and Banting for their discovery of insulin to treat diabetes -
Insulin's Amino Acid Sequence Found
Insulin was the first protein where the amino acid sequence was determined leading to the Nobel Prize award to Fred Sanger -
Foundations of Synthetic Insulin Production
Foundation for synthetic production of insulin was founded -
Start of Synthetic Insulin Production
Synthetic insulin production began and can be used to make different forms of insulin for various purposes