King Philip II

King Philip II marries his cousin Maria of Portugal

Nov 15, 1543

Maria of Portugal, wife of King Philip II, dies

Jul 12, 1545

Maria of Portugal dies while giving birth to their ill-fated Don Carlos.

King Philip II married his 2nd wife, Mary I of England

Jul 25, 1554

Mary I of England, King Philip II 2nd wife, dies

Nov 17, 1558

Mary I of England dies at the St. James Palace due to an influenza epidemic at age 42.

King Philip II marries his 3rd wife, Elizabeth of Valois

Jun 22, 1559

King Philip II built the Palace of El Escorial

May 23, 1563

King Philip II built the palace of El Escorial in Madrid on the slopes of the Sierra de Guadarrama.

Elizabeth of Valois and King Philip II had their first child, Isabella Clara Eugenia

Aug 12, 1566

Elizabeth of Valois and King Philip II have birth to their 2nd child, Catherine Micaela

Oct 10, 1567

Elizabeth dies

Oct 3, 1568

Elizabeth of Valois had a miscarriage and died the same day as well as her newborn infant daughter.

King Philip II marries his 4th wife, Anna of Austria

Nov 14, 1570

Anna of Austria died

Oct 26, 1580

Anna of Austria died due to heart failure 8 months after giving birth to her last child.